glutathion s transferase Glutathione - an overview Overexpression of Glutathione S-Transferases in

System Xc - , which is a heterodimeric transmembrane transporter consisting of the light chain xCT (SLC7A11) and heavy chain 4F2hc (SLC3A2) (Koppula et al., 2018), facilitates the exchange of cystine and glutamate at a 1:1 ratio (Liu et al., 2021)

It's a very strong antioxidant thats naturally produced by the liver and used daily by the body

GSH-conjugated UV filters increase with a corresponding decrease in free GSH, and therefore may contribute to a decreased capacity for nuclear GSH to protect lens proteins from cross-linking and insolubilisation (110)

Given the detrimental effects of such hepatotoxic agents, there is an increasing interest in natural antioxidants in foods high in non-enzymatic antioxidants including Vitamin C, and E, Carotenoids, Flavonoids, and polyphenols that can provide protective effects against liver damage (4)